Association Between udp-glucuronosyltransferase 1a1 (ugt1a1) Gene Polymorphism, (c.-3279t>g) and Phototherapy among Glucose-6-Phosphate Dehydrogenase (g6pd)-Deficient Neonates
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چکیده
منابع مشابه
Hyperbilirubinemia among African American, glucose-6-phosphate dehydrogenase-deficient neonates.
BACKGROUND Although glucose-6-phosphate dehydrogenase (G-6-PD) deficiency is prevalent in African Americans, their risk of associated neonatal hyperbilirubinemia has not been prospectively studied. OBJECTIVE To compare hemolysis and the risk of hyperbilirubinemia among African American, G-6-PD-deficient neonates (study group) and G-6-PD-normal control subjects. METHODS Consecutive, healthy,...
متن کاملEffect of hemolysis and hyperbilirubinemia in glucose-6-phosphate dehydrogenase-deficient neonates
Objective: Recently, the role of hemolysis in the pathophysiology of hyperbilirubinemia in glucose-6phosphate dehydrogenase (G6PD) deficient neonates has been questioned and decreased bilirubin conjugation has been suggested. We conducted a study to evaluate the effect of hemolysis on these neonates at the 17-Shahrivar Children Hospital in Rasht. Methods: In this cross-sectional s...
متن کاملMOLECULAR IDENTIFICATION OF THE MOST PREVALENT MUTATION OF GLUCOSE-6-PHOSPHATE DEHYDROGENASE (G6PD) GENE IN DEFICIENT PATIENTS IN GILAN PROVINCE
Glucose-6-Phosphate Dehydrogenase (G6PD) is a cytosolic enzyme which its main function is to produce NADPH in the red blood cells by controlling the step from Glucose-6-Phosphate to 6-Phospho gluconate in the pentose phosphate pathway. G6PD deficiency is the most common X-chromosome linked hereditary enzymopathy in the world, that result in reduced enzyme activity and more than 125 different mu...
متن کاملcorrelation between hemolysis and jaundice in glucose 6-phosphate dehydrogenase deficient neonates
glucose 6-phosphate dehydrogenase (g6pd) deficiency is an enzyme deficiency of the red blood cells and the most important disease of hexose monophosphate pathway. the role of hemolysis in the pathophysiology of neonatal jaundice due to g6pd deficiency is in contencious. our aim is to study the role of hemolysis in neonatal jaundice associated with g6pd deficiency. this prospective descriptive s...
متن کاملRelation between Neonatal Icter and Gilbert Syndrome in Gloucose-6-Phosphate Dehydrogenase Deficient Subjects.
BACKGROUND AND AIM The pathogenesis of neonatal hyperbilirubinemia hasn't been completely defined in Gloucose-6-Phosphate Dehydrogenase (G6PD) deficient newborns. The aim of this study was to detect the relationship between Gilbert's syndrome and hyperbilirubinemia in Gloucose-6-Phosphate Dehydrogenase (G6PD) deficient neonates. MATERIALS AND METHODS This case-control study was conducted in A...
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ژورنال
عنوان ژورنال: Biomedical Journal of Scientific & Technical Research
سال: 2018
ISSN: 2574-1241
DOI: 10.26717/bjstr.2018.02.000714